The endocannabinoid 2-arachidonoylglycerol is released and transported on demand via extracellular microvesicles

Proceedings of the National Academy of Sciences, Volume 122, Issue 8, February 2025.
SignificanceEndocannabinoids (eCB) are lipid neurotransmitters that play a critical role in brain function by activating the cannabinoid CB1 receptor. Unlike classical neurotransmitters, their storage and release mechanisms have remained elusive, leading …
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