The kinesin KIF3AC recycles endocytosed integrin to polarize new adhesion formation toward the leading edge

Proceedings of the National Academy of Sciences, Volume 122, Issue 30, July 2025.
SignificanceThis study reveals that the heterodimeric kinesin-2 motor kinesin superfamily (KIF)3AC and its adaptor Rab coupling protein (RCP) are crucial for polarized formation of focal adhesions (FAs) at the front of migrating fibroblasts…
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